BDBM50187989 4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)ethynyl)-6-ethoxyquinoline-3-carbonitrile::CHEMBL211647

SMILES CCOc1cc2c(Nc3cc(OC)c(Cl)cc3Cl)c(cnc2cc1C#Cc1cccc(CN(C)C)n1)C#N

InChI Key InChIKey=VVOBMXWTLSJAEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187989   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187989(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-((di...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187989(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-((di...)
Affinity DataIC50: 86nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed