BDBM50188030 2-methoxy-3-(1-((5-methyl-2-phenyloxazol-4-yl)methyl)-1H-indol-5-yl)propanoic acid::CHEMBL213902

SMILES COC(Cc1ccc2n(Cc3nc(oc3C)-c3ccccc3)ccc2c1)C(O)=O

InChI Key InChIKey=ZYZXCPVWUZRARY-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188030   

TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188030BDBM50188030(2-methoxy-3-(1-((5-methyl-2-phenyloxazol-4-yl)meth...)
Affinity DataIC50: 318nMAssay Description:Binding affinity to PPARgamma by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188030BDBM50188030(2-methoxy-3-(1-((5-methyl-2-phenyloxazol-4-yl)meth...)
Affinity DataEC50:  350nMAssay Description:Activity at PPARalpha by luciferase reporter gene transactivation assay relative to farglitazarMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188030BDBM50188030(2-methoxy-3-(1-((5-methyl-2-phenyloxazol-4-yl)meth...)
Affinity DataIC50: 363nMAssay Description:Binding affinity to PPARalpha by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188030BDBM50188030(2-methoxy-3-(1-((5-methyl-2-phenyloxazol-4-yl)meth...)
Affinity DataEC50:  1.10E+3nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay relative to edaglitazoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188030BDBM50188030(2-methoxy-3-(1-((5-methyl-2-phenyloxazol-4-yl)meth...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at PPARdelta by luciferase reporter gene transactivation assay relative to GW 501516More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed