BDBM50188049 1-(2-(2-chlorophenyl)-1-phenylethyl)piperazine::CHEMBL213287::CHEMBL534942

SMILES Clc1ccccc1CC(N1CCNCC1)c1ccccc1

InChI Key InChIKey=SDLVJPBOBLQFEW-UHFFFAOYSA-N

Data  22 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50188049   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]5-HT reuptake at 5HT transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]5-HT reuptake at 5HT transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]5-HT reuptake at 5HT transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]NA reuptake at NA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]NA reuptake at NA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]NA reuptake at NA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 500nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 500nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [3H]DA reuptake at DA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of DA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [3H]DA reuptake at DA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [3H]DA reuptake at DA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed