BDBM50188050 2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile::CHEMBL213035

SMILES N#Cc1ccccc1CC(N1CCNCC1)c1ccccc1

InChI Key InChIKey=FCHUPCOGZXEFDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188050   

LigandPNGBDBM50188050(2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile |...)
Affinity DataIC50: 73nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188050(2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile |...)
Affinity DataIC50: 87nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed