BDBM50188107 (S)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine hydrochloride::CHEMBL540107

SMILES CCOc1ccccc1C[C@H](N1CCNCC1)c1ccccc1

InChI Key InChIKey=CVFBVSUFNWOPLD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188107   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188107((S)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of [3H]5-HT reuptake at 5HT transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188107((S)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [3H]NA reuptake at NA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188107((S)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of [3H]DA reuptake at DA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188107((S)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188107((S)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed