BDBM50188340 4-(2-chloro-5-hydroxy-phenyl)-8-[4-(4-methyl-piperazin-1-yl)-phenylamino]-1,2-dihydro-3a,7,9,9b-tetraaza-cyclopenta[a]naphthalen-3-one::CHEMBL213356

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3C=C(N4N(CCC4=O)c3n2)c2cc(O)ccc2Cl)cc1

InChI Key InChIKey=PAMDZUAYRSYBHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188340   

TargetTyrosine-protein kinase Lck(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188340(4-(2-chloro-5-hydroxy-phenyl)-8-[4-(4-methyl-piper...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant Lck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188340(4-(2-chloro-5-hydroxy-phenyl)-8-[4-(4-methyl-piper...)
Affinity DataIC50: 456nMAssay Description:Inhibition of human recombinant Hck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188340(4-(2-chloro-5-hydroxy-phenyl)-8-[4-(4-methyl-piper...)
Affinity DataIC50: 764nMAssay Description:Inhibition of human recombinant Src in presence of 10 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed