BDBM50188342 4-(2,6-dichloro-phenyl)-8-(4-morpholin-4-yl-phenylamino)-1,2-dihydro-3a,7,9,9b-tetraaza-cyclopenta[a]naphthalen-3-one::CHEMBL213745

SMILES Clc1cccc(Cl)c1C1=Cc2cnc(Nc3ccc(cc3)N3CCOCC3)nc2N2CCC(=O)N12

InChI Key InChIKey=GZZUDLULILLTCZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188342   

TargetTyrosine-protein kinase Lck(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188342(4-(2,6-dichloro-phenyl)-8-(4-morpholin-4-yl-phenyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant Lck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188342(4-(2,6-dichloro-phenyl)-8-(4-morpholin-4-yl-phenyl...)
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant Src in presence of 10 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188342(4-(2,6-dichloro-phenyl)-8-(4-morpholin-4-yl-phenyl...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant Hck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed