BDBM50188357 4-(2,6-dichloro-phenyl)-8-[4-(2-dimethylamino-ethyl)-phenylamino]-1,2-dihydro-3a,7,9,9b-tetraaza-cyclopenta[a]naphthalen-3-one::CHEMBL441361

SMILES CN(C)CCc1ccc(Nc2ncc3C=C(N4N(CCC4=O)c3n2)c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=QDKWSHGBLDBHFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188357   

TargetTyrosine-protein kinase Lck(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188357(4-(2,6-dichloro-phenyl)-8-[4-(2-dimethylamino-ethy...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant Lck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed