BDBM50188389 CHEMBL210465::N-(3,4-dimethoxyphenethyl)-4,7,7-trimethyl-2,3-dioxobicyclo[2.2.1]heptane-1-carboxamide

SMILES COc1ccc(CCNC(=O)C23CCC(C)(C(=O)C2=O)C3(C)C)cc1OC

InChI Key InChIKey=WKJZKNFGZORWFP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188389   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(N-(3,4-dimethoxyphenethyl)-4,7,7-trimethyl-2,3-dio...)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(N-(3,4-dimethoxyphenethyl)-4,7,7-trimethyl-2,3-dio...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of 11-beta-HSD1-dependent cortisone conversion to cortisol in mouse intact 3T3 L1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(N-(3,4-dimethoxyphenethyl)-4,7,7-trimethyl-2,3-dio...)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of 11-beta-HSD1-dependent cortisone conversion to cortisol in mouse intact C2C12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(N-(3,4-dimethoxyphenethyl)-4,7,7-trimethyl-2,3-dio...)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(N-(3,4-dimethoxyphenethyl)-4,7,7-trimethyl-2,3-dio...)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human recombinant 17betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed