BDBM50188474 CHEMBL426863::N-[4-[4-(2,3-difluorophenyl)piperazin-1-yl]butyl][2.2]-paracyclophane-4-carboxamide

SMILES Fc1cccc(N2CCN(CCCCNC(=O)c3cc4CCc5ccc(CCc3cc4)cc5)CC2)c1F

InChI Key InChIKey=DHFUVVTYPXJZAP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50188474   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188474(N-[4-[4-(2,3-difluorophenyl)piperazin-1-yl]butyl][...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188474(N-[4-[4-(2,3-difluorophenyl)piperazin-1-yl]butyl][...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188474(N-[4-[4-(2,3-difluorophenyl)piperazin-1-yl]butyl][...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]spiperone from human D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188474(N-[4-[4-(2,3-difluorophenyl)piperazin-1-yl]butyl][...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]spiperone from human D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188474(N-[4-[4-(2,3-difluorophenyl)piperazin-1-yl]butyl][...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor of porcine cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188474(N-[4-[4-(2,3-difluorophenyl)piperazin-1-yl]butyl][...)
Affinity DataKi:  570nMAssay Description:Displacement of [3H]SCH 23390 from D1 receptor of porcine striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed