BDBM50188612 CHEMBL208818::N-n-hexyl-N'-[2-(4-methylphenoxy)-5-nitrobenzenesulfonyl]urea

SMILES CCCCCCNC(=O)NS(=O)(=O)c1cc(ccc1Oc1ccc(C)cc1)[N+]([O-])=O

InChI Key InChIKey=QZJDWMYQUUOVPQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50188612   

TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50188612(N-n-hexyl-N'-[2-(4-methylphenoxy)-5-nitrobenzenesu...)
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50188612(N-n-hexyl-N'-[2-(4-methylphenoxy)-5-nitrobenzenesu...)
Affinity DataIC50: 1.58nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50188612(N-n-hexyl-N'-[2-(4-methylphenoxy)-5-nitrobenzenesu...)
Affinity DataIC50: 58.5nMAssay Description:Activity at TPbeta (long isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50188612(N-n-hexyl-N'-[2-(4-methylphenoxy)-5-nitrobenzenesu...)
Affinity DataIC50: 526nMAssay Description:Activity at TPalpha (short isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed