BDBM50189017 (S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propanoyl)-3-(2-aminoethyl)-2-oxopiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide::CHEMBL214770

SMILES CNC(=O)[C@H](Cc1ccc2ccccc2c1)N1CCN([C@@H](CCN)C1=O)C(=O)[C@H](N)Cc1ccc(F)cc1

InChI Key InChIKey=NODFZMIIOOJXQA-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50189017   

TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189017((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataEC50:  45nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189017((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataEC50:  45nMAssay Description:Agonist activity at human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189017((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  189nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189017((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  189nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189017((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  4.12E+3nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189017((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  4.12E+3nMAssay Description:Binding affinity to human MC3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189017((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  5.82E+3nMAssay Description:Binding affinity to human MC1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189017((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  5.82E+3nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed