BDBM50189549 CHEMBL3827756
SMILES CCCCCCSc1nc(O)cc(O)n1
InChI Key InChIKey=UYXOAKRMLQKLQX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50189549
Affinity DataKi: 0.219nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
Affinity DataEC50: 144nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated...More data for this Ligand-Target Pair
Affinity DataEC50: 213nMAssay Description:Agonist activity at recombinant human GPR84 stably expressed in HEK293 cells co-expressing Galpha16 assessed as increase in intracellular calcium mob...More data for this Ligand-Target Pair
Affinity DataEC50: 0.790nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at GPR84 in mouse bone-marrow-derived neutrophils assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liquid ...More data for this Ligand-Target Pair
Affinity DataEC50: 597nMAssay Description:Agonist activity at recombinant human GPR84 expressed in HEK293 cells assessed as beta-arrestin 2 recruitment measured after 20 mins by luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 8.13E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO-K1 cells assessed as induction of beta-arrestin recruitment by luminescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Agonist activity at human Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as stimulation of [35S]GTPgammaS binding ...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as stimulation of [35S]GTPgammaS binding ...More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at GPR84 in LPS-treated human THP-1 cell membrane assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liquid ...More data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liq...More data for this Ligand-Target Pair
Affinity DataEC50: 139nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 134nMAssay Description:Agonist activity at recombinant human GPR84 stably expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of forskolin-induced cAMP ...More data for this Ligand-Target Pair