BDBM50189571 CHEMBL383873::[3-(4-bromo-phenyl)-7-aza-tricyclo[5.3.0.0*4,8*]dec-(5E)-ylidene]-acetic acid methyl ester

SMILES COC(=O)\C=C1\CN2C3CCC2C1C(C3)c1ccc(Br)cc1

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189571   

TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50189571([3-(4-bromo-phenyl)-7-aza-tricyclo[5.3.0.0*4,8*]de...)
Affinity DataKi:  2.94nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50189571([3-(4-bromo-phenyl)-7-aza-tricyclo[5.3.0.0*4,8*]de...)
Affinity DataKi:  5.63nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50189571([3-(4-bromo-phenyl)-7-aza-tricyclo[5.3.0.0*4,8*]de...)
Affinity DataKi:  12.5nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed