BDBM50190062 CHEMBL213336::N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-2,6-dimethyl-benzamide

SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2c(C)cccc2C)c2ccccc12

InChI Key InChIKey=IYRXIXGRSIJDNI-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50190062   

Target5-hydroxytryptamine receptor 2A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190062(N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190062(N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190062(N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190062(N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b...)
Affinity DataKi:  31nMAssay Description:Binding affinity at dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190062(N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b...)
Affinity DataKi:  287nMAssay Description:Displacement of [3H]methylspiperone from dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190062(N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b...)
Affinity DataKi:  287nMAssay Description:Binding affinity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190062(N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b...)
Affinity DataKi:  287nMAssay Description:Displacement of [3H]methylspiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190062(N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b...)
Affinity DataKi:  791nMAssay Description:Binding affinity at adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190062(N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b...)
Affinity DataKi:  1.87E+3nMAssay Description:Binding affinity at dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed