BDBM50190526 (3S)-1,9-dibenzyl-3-(2-methylpropyl)-1,4,9-triazaspiro[5.5]-undeca-2,5-dione hydrochloride::CHEMBL539854

SMILES CC(C)C[C@@H]1NC(=O)C2(CCN(Cc3ccccc3)CC2)N(Cc2ccccc2)C1=O

InChI Key InChIKey=HJMJXSLZAFZRFV-QHCPKHFHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190526   

TargetC-C chemokine receptor type 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190526((3S)-1,9-dibenzyl-3-(2-methylpropyl)-1,4,9-triazas...)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity against human recombinant CCR2 expressed in CHO cells assessed as inhibition of human MCP1-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190526((3S)-1,9-dibenzyl-3-(2-methylpropyl)-1,4,9-triazas...)
Affinity DataIC50:  3.20E+3nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190526((3S)-1,9-dibenzyl-3-(2-methylpropyl)-1,4,9-triazas...)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity against human recombinant CCR4 expressed in CHO cells assessed as inhibition of human MCD-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190526((3S)-1,9-dibenzyl-3-(2-methylpropyl)-1,4,9-triazas...)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity against human recombinant CXCR4 expressed in CHO cells assessed as inhibition of human SDF1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed