BDBM50190544 1-((2R,4S,5R)-4-fluoro-5-(trityloxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione::2,3-DEOXY-3-FLUORO-5-O-TRITYLURIDINE::CHEMBL209720

SMILES F[C@H]1C[C@@H](O[C@@H]1COC(c1ccccc1)(c1ccccc1)c1ccccc1)n1ccc(=O)[nH]c1=O

InChI Key InChIKey=GJNIPWYJQUGERM-BFLUCZKCSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190544   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum (isolate 3D7))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50190544(1-((2R,4S,5R)-4-fluoro-5-(trityloxymethyl)-tetrahy...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Instituto De Parasitolog£A Y Biomedicina L£Pez-Neyra

Curated by ChEMBL
LigandPNGBDBM50190544(1-((2R,4S,5R)-4-fluoro-5-(trityloxymethyl)-tetrahy...)
Affinity DataKi:  4.57E+5nMAssay Description:Inhibition of human dUTPase using dUTP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Instituto De Parasitolog£A Y Biomedicina L£Pez-Neyra

Curated by ChEMBL
LigandPNGBDBM50190544(1-((2R,4S,5R)-4-fluoro-5-(trityloxymethyl)-tetrahy...)
Affinity DataKi:  4.57E+5nMAssay Description:Inhibition of human recombinant dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed