BDBM50191104 CHEMBL214748::N-((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)-2-(1H-imidazol-4-yl)-N-methylacetamide

SMILES C[C@@H](O[C@H]1CC[C@H]([C@@H]1c1ccc(F)cc1)N(C)C(=O)Cc1cnc[nH]1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=XIRJXRDKXDGDJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191104   

TargetSubstance-P receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191104(N-((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)ph...)
Affinity DataIC50: 0.270nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed