BDBM50191331 4,5,6,7,8,9,10,11,12,13,15,19a,20,21,22,23,24,24a-octadecahydro-25-methyl-16,19-etheno-21,24-imino-1H-cyclohept[c][1,9]-oxaazacycloheneicosine-3,14-dione::CHEMBL379755

SMILES CN1C2CCC1C1COC(=O)CCCCCCCCCCC(=O)Nc3ccc(cc3)C1C2

InChI Key

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50191331   

TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191331(4,5,6,7,8,9,10,11,12,13,15,19a,20,21,22,23,24,24a-...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191331(4,5,6,7,8,9,10,11,12,13,15,19a,20,21,22,23,24,24a-...)
Affinity DataIC50: 390nMAssay Description:Displacement of [3H]WIN-35428 from human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191331(4,5,6,7,8,9,10,11,12,13,15,19a,20,21,22,23,24,24a-...)
Affinity DataKi:  1.16E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191331(4,5,6,7,8,9,10,11,12,13,15,19a,20,21,22,23,24,24a-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191331(4,5,6,7,8,9,10,11,12,13,15,19a,20,21,22,23,24,24a-...)
Affinity DataIC50: 2.32E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed