BDBM50191332 20-methyl-4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-3Hspiro[16,19-epimino-11,14-ethenocyclohepta[c][1,9]oxazacyclohexadecine-6,9'-fluorene]-3,9(1H)-dione::CHEMBL378483

SMILES CN1C2CCC1C1COC(=O)CCC3(CCC(=O)Nc4ccc(cc4)C1C2)c1ccccc1-c1ccccc31

InChI Key

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50191332   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191332(20-methyl-4,5,7,8,10,14a,15,16,17,18,19,19a-dodeca...)
Affinity DataIC50: 290nMAssay Description:Displacement of [3H]WIN-35428 from human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191332(20-methyl-4,5,7,8,10,14a,15,16,17,18,19,19a-dodeca...)
Affinity DataKi:  490nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191332(20-methyl-4,5,7,8,10,14a,15,16,17,18,19,19a-dodeca...)
Affinity DataIC50: 980nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191332(20-methyl-4,5,7,8,10,14a,15,16,17,18,19,19a-dodeca...)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed