BDBM50191335 4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-methyl-11,-14-etheno-16,19-imino-3H-cyclohept[n][1,5,9]oxathiaazacyclohexadecine-3,9(1H)-dione::CHEMBL378243

SMILES CN1C2CCC1C1COC(=O)CCSCCC(=O)Nc3ccc(cc3)C1C2

InChI Key

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50191335   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191335(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]WIN-35428 from human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191335(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191335(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataIC50: 990nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191335(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataKi:  1.65E+3nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191335(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataIC50: 6.73E+3nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed