BDBM50191336 5,6,7,8,9,10,11,12,13,14,16,20a,21,22,23,24,25,25a-octadecahydro-16,26-dimethyl-17,20-etheno-22,25-iminocyclohept[c][1,9]-oxaazacyclodocosine-3(1H,4H)-one::CHEMBL379181

SMILES CN1C2CCC1C1COC(=O)CCCCCCCCCCCN(C)c3ccc(cc3)C1C2

InChI Key

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50191336   

TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191336(5,6,7,8,9,10,11,12,13,14,16,20a,21,22,23,24,25,25a...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191336(5,6,7,8,9,10,11,12,13,14,16,20a,21,22,23,24,25,25a...)
Affinity DataIC50: 450nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191336(5,6,7,8,9,10,11,12,13,14,16,20a,21,22,23,24,25,25a...)
Affinity DataIC50: 490nMAssay Description:Displacement of [3H]WIN-35428 from human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191336(5,6,7,8,9,10,11,12,13,14,16,20a,21,22,23,24,25,25a...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed