BDBM50191337 4,5,6,7,8,9,11,15a,16,17,18,19,20,20a-tetradecahydro-21-methyl-12,15-etheno-17,20-imino-1H-cyclohept[c][1,9]oxaazacycloheptadecine-3,10-dione::CHEMBL385359

SMILES CN1C2CCC1C1COC(=O)CCCCCCC(=O)Nc3ccc(cc3)C1C2

InChI Key

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50191337   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191337(4,5,6,7,8,9,11,15a,16,17,18,19,20,20a-tetradecahyd...)
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]WIN-35428 from human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191337(4,5,6,7,8,9,11,15a,16,17,18,19,20,20a-tetradecahyd...)
Affinity DataKi:  513nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191337(4,5,6,7,8,9,11,15a,16,17,18,19,20,20a-tetradecahyd...)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191337(4,5,6,7,8,9,11,15a,16,17,18,19,20,20a-tetradecahyd...)
Affinity DataIC50: 2.09E+3nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191337(4,5,6,7,8,9,11,15a,16,17,18,19,20,20a-tetradecahyd...)
Affinity DataIC50: 3.04E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed