BDBM50191338 5,6,7,8,9,10,11,12,14,18a,19,20,21,22,23,23a-hexadecahydro-14,24-dimethyl-15,18-etheno-5620,23-iminocyclohept[c][1,9]oxaazacycloeicosine-3(1H,4H)-one::CHEMBL380056

SMILES CN1C2CCC1C1COC(=O)CCCCCCCCCN(C)c3ccc(cc3)C1C2

InChI Key

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50191338   

TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191338(5,6,7,8,9,10,11,12,14,18a,19,20,21,22,23,23a-hexad...)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191338(5,6,7,8,9,10,11,12,14,18a,19,20,21,22,23,23a-hexad...)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]WIN-35428 from human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191338(5,6,7,8,9,10,11,12,14,18a,19,20,21,22,23,23a-hexad...)
Affinity DataIC50: 380nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191338(5,6,7,8,9,10,11,12,14,18a,19,20,21,22,23,23a-hexad...)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191338(5,6,7,8,9,10,11,12,14,18a,19,20,21,22,23,23a-hexad...)
Affinity DataIC50: 2.13E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed