BDBM50191340 4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-methyl-11,-14-theno-16,19-iminocyclohept[c][1,9]oxaazacyclohexadecine-3,6,9(1H)-trione::CHEMBL379333

SMILES CN1C2CCC1C1COC(=O)CCC(=O)CCC(=O)Nc3ccc(cc3)C1C2

InChI Key

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50191340   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191340(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataIC50: 160nMAssay Description:Displacement of [3H]WIN-35428 from human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191340(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataKi:  710nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191340(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataKi:  1.23E+3nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191340(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50191340(4,5,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...)
Affinity DataIC50: 5.01E+3nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed