BDBM50191551 (2R,4R)-1-((R)-2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-3-phenylpropanoyl)-N-(2-guanidinoethyl)-4-(naphthalen-2-ylmethoxy)pyrrolidine-2-carboxamide::CHEMBL209587

SMILES N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N1C[C@@H](C[C@@H]1C(=O)NCCN=C(N)N)OCc1ccc2ccccc2c1

InChI Key InChIKey=DNDWQJKQEQLRTQ-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50191551   

TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191551((2R,4R)-1-((R)-2-((S)-2-amino-3-(1H-imidazol-4-yl)...)
Affinity DataKi:  15nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191551((2R,4R)-1-((R)-2-((S)-2-amino-3-(1H-imidazol-4-yl)...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human MC1R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191551((2R,4R)-1-((R)-2-((S)-2-amino-3-(1H-imidazol-4-yl)...)
Affinity DataEC50:  249nMAssay Description:Agonist activity at human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191551((2R,4R)-1-((R)-2-((S)-2-amino-3-(1H-imidazol-4-yl)...)
Affinity DataEC50:  266nMAssay Description:Agonist activity at human MC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191551((2R,4R)-1-((R)-2-((S)-2-amino-3-(1H-imidazol-4-yl)...)
Affinity DataKi:  703nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191551((2R,4R)-1-((R)-2-((S)-2-amino-3-(1H-imidazol-4-yl)...)
Affinity DataKi:  760nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed