BDBM50191578 (S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide::CHEMBL375440

SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H]-1-[#6]-[#6@H](-[#6]-[#7]-1-[#6](=O)-[#6@@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1)-[#8]-[#6]-c1ccc2ccccc2c1

InChI Key InChIKey=DEQSFWKJAFMEST-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50191578   

TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
Affinity DataKi:  46nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human MC1R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
Affinity DataKi:  55nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
Affinity DataKi:  219nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
Affinity DataEC50:  593nMAssay Description:Agonist activity at human MC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed