BDBM50191723 CHEMBL215777::N-(4-(trifluoromethyl)phenyl)-5-(3-(trifluoromethyl)pyridin-2-yl)pyrimidine-2-carboxamide

SMILES FC(F)(F)c1ccc(NC(=O)c2ncc(cn2)-c2ncccc2C(F)(F)F)cc1

InChI Key InChIKey=FCWQEAGWGADNJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191723   

LigandPNGBDBM50191723(N-(4-(trifluoromethyl)phenyl)-5-(3-(trifluoromethy...)
Affinity DataIC50: 42nMAssay Description:Antagonist activity against capsaicin-activated human VR1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50191723(N-(4-(trifluoromethyl)phenyl)-5-(3-(trifluoromethy...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity against low pH(5.0-5.5)-activated rat VR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed