BDBM50191906 CHEMBL215512::N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3ylamino)-2-oxoethyl)-1,1-dioxido-5-oxo-1,4-thiazepan-6-yl)-2-naphthamide

SMILES OC1OC(=O)C[C@@H]1NC(=O)CN1CCS(=O)(=O)C[C@H](NC(=O)c2ccc3ccccc3c2)C1=O

InChI Key InChIKey=IJEMUOZOHBMZSW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191906   

TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191906(N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3...)
Affinity DataIC50: 150nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191906(N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191906(N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed