BDBM50192133 2-(4-(benzyl(2,2,2-trifluoroethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214777

SMILES OC(c1ccc(cc1)N(Cc1ccccc1)CC(F)(F)F)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=MUUGHUBMRJKYSW-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50192133   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192133(2-(4-(benzyl(2,2,2-trifluoroethyl)amino)phenyl)-1,...)
Affinity DataIC50:  60nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192133(2-(4-(benzyl(2,2,2-trifluoroethyl)amino)phenyl)-1,...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192133(2-(4-(benzyl(2,2,2-trifluoroethyl)amino)phenyl)-1,...)
Affinity DataEC50:  900nMAssay Description:Transactivation of LXRalpha by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192133(2-(4-(benzyl(2,2,2-trifluoroethyl)amino)phenyl)-1,...)
Affinity DataEC50:  200nMAssay Description:Transactivation of LXRbeta by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed