BDBM50192167 CHEMBL214726::N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-yl)benzamide::N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide

SMILES Fc1ccc2cc(CN3CCC(CC3)NC(=O)c3ccccc3)ccc2c1

InChI Key InChIKey=KMIVFOQFRIPVDV-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192167   

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192167(N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-...)
Affinity DataIC50: 109nMAssay Description:Inhibition of MCH-mediated calcium release by CHO cells expressing human MCH-R1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192167(N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-...)
Affinity DataKi:  125nMAssay Description:Binding activity against human MCH-R1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50192167(N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at CCR3 expressed in B300-19 cells assessed as inhibition of eotaxin-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed