BDBM50192215 3-(4-tert-butylphenyl)-4-cyano-5-(propylthio)thiophene-2-carboxylic acid::CHEMBL538396

SMILES CCCSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=HQHWQUUGOSGZGE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192215   

TargetGlutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192215(3-(4-tert-butylphenyl)-4-cyano-5-(propylthio)thiop...)
Affinity DataEC50:  2.89E+3nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assessed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192215(3-(4-tert-butylphenyl)-4-cyano-5-(propylthio)thiop...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assessed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed