BDBM50192367 4-(2-chlorophenyl)-6-ethyl-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL379825

SMILES CCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1Cl

InChI Key InChIKey=PPKWYAYCBJKWOR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192367   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50192367(4-(2-chlorophenyl)-6-ethyl-9-hydroxypyrrolo[3,4-c]...)
Affinity DataIC50:  120nMAssay Description:Inhibition at human Chk1 in presence of 4 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50192367(4-(2-chlorophenyl)-6-ethyl-9-hydroxypyrrolo[3,4-c]...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50192367(4-(2-chlorophenyl)-6-ethyl-9-hydroxypyrrolo[3,4-c]...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human Wee1 in presence of 9.5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed