BDBM50193188 (S)-N-(4-(trifluoromethyl)benzyl)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carboxamide::CHEMBL218836

SMILES FC(F)(F)c1ccc(CNC(=O)N2CCC[C@H]2CN2CCCC2)cc1

InChI Key InChIKey=WAYVRIDOONUDTD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193188   

TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50193188((S)-N-(4-(trifluoromethyl)benzyl)-2-(pyrrolidin-1-...)
Affinity DataKi:  162nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50193188((S)-N-(4-(trifluoromethyl)benzyl)-2-(pyrrolidin-1-...)
Affinity DataKi:  162nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50193188((S)-N-(4-(trifluoromethyl)benzyl)-2-(pyrrolidin-1-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed