BDBM50193198 (4-cyclopropylpiperazin-1-yl)(isoindolin-2-yl)methanone::CHEMBL373860

SMILES O=C(N1Cc2ccccc2C1)N1CCN(CC1)C1CC1

InChI Key InChIKey=PWWZWUNVIFMMLP-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193198   

TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50193198((4-cyclopropylpiperazin-1-yl)(isoindolin-2-yl)meth...)
Affinity DataKi:  45nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50193198((4-cyclopropylpiperazin-1-yl)(isoindolin-2-yl)meth...)
Affinity DataKi:  45nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50193198((4-cyclopropylpiperazin-1-yl)(isoindolin-2-yl)meth...)
Affinity DataIC50: 5.25E+4nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed