BDBM50193291 (Z)-2-[4-(3-hydroxyimino-3-phenylpropyl)piperazin-1-yl]nicotinonitrile::CHEMBL215670::CHEMBL438961

SMILES O=NC(CCN1CCN(CC1)c1ncccc1C#N)c1ccccc1

InChI Key InChIKey=ZLLJRDAILKKIPA-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50193291   

TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193291(CHEMBL215670 | CHEMBL438961 | (Z)-2-[4-(3-hydroxyi...)
Affinity DataEC50:  18nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193291(CHEMBL215670 | CHEMBL438961 | (Z)-2-[4-(3-hydroxyi...)
Affinity DataEC50:  20nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193291(CHEMBL215670 | CHEMBL438961 | (Z)-2-[4-(3-hydroxyi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193291(CHEMBL215670 | CHEMBL438961 | (Z)-2-[4-(3-hydroxyi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193291(CHEMBL215670 | CHEMBL438961 | (Z)-2-[4-(3-hydroxyi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193291(CHEMBL215670 | CHEMBL438961 | (Z)-2-[4-(3-hydroxyi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed