BDBM50193308 (Z)-2-hydroxy-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)-propan-1-one oxime::CHEMBL211463::CHEMBL215723

SMILES Cc1cccc(c1)C(NO)C(=O)CN1CCN(CC1)c1ccccn1

InChI Key InChIKey=QTFPAMABGWDWIR-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50193308   

TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193308(CHEMBL215723 | CHEMBL211463 | (Z)-2-hydroxy-3-(4-p...)
Affinity DataEC50:  4.90nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193308(CHEMBL215723 | CHEMBL211463 | (Z)-2-hydroxy-3-(4-p...)
Affinity DataEC50:  44.8nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193308(CHEMBL215723 | CHEMBL211463 | (Z)-2-hydroxy-3-(4-p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193308(CHEMBL215723 | CHEMBL211463 | (Z)-2-hydroxy-3-(4-p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193308(CHEMBL215723 | CHEMBL211463 | (Z)-2-hydroxy-3-(4-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193308(CHEMBL215723 | CHEMBL211463 | (Z)-2-hydroxy-3-(4-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed