BDBM50193363 (Z)-2-methoxy-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)-propan-1-one O-methyloxime::CHEMBL211623::CHEMBL212028

SMILES COC(CN1CCN(CC1)c1ccccn1)C(N=O)c1cccc(C)c1

InChI Key InChIKey=WJBXZGTUKWEVIU-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50193363   

TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193363(CHEMBL212028 | CHEMBL211623 | (Z)-2-methoxy-3-(4-p...)
Affinity DataEC50:  34.5nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193363(CHEMBL212028 | CHEMBL211623 | (Z)-2-methoxy-3-(4-p...)
Affinity DataEC50:  5.37E+3nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193363(CHEMBL212028 | CHEMBL211623 | (Z)-2-methoxy-3-(4-p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193363(CHEMBL212028 | CHEMBL211623 | (Z)-2-methoxy-3-(4-p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193363(CHEMBL212028 | CHEMBL211623 | (Z)-2-methoxy-3-(4-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193363(CHEMBL212028 | CHEMBL211623 | (Z)-2-methoxy-3-(4-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed