BDBM50193989 CHEMBL221976::N-((S)-1-(4-fluorophenyl)ethyl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)pyrimidin-4-amine

SMILES C[C@H](Nc1ccnc(n1)-n1cnc2ccncc12)c1ccc(F)cc1

InChI Key InChIKey=PPOFTHNFMSSOFB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193989   

TargetTyrosine-protein kinase JAK2(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193989(N-((S)-1-(4-fluorophenyl)ethyl)-2-(3H-imidazo[4,5-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193989(N-((S)-1-(4-fluorophenyl)ethyl)-2-(3H-imidazo[4,5-...)
Affinity DataIC50: 92nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed