BDBM50194059 5-4-2-chloro-3-trifluoromethyl)phenoxy)-3-fluorophenylamino)-3-hydroxy-N-1-hydroxypropan-2-yl)isothiazole-4-carboximidamide::CHEMBL217414
SMILES CC(CO)N=C(N)c1c(Nc2ccc(Oc3cccc(c3Cl)C(F)(F)F)c(F)c2)s[nH]c1=O
InChI Key InChIKey=FZBHRCOPPUGRFO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50194059
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataEC50: 88nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair