BDBM50194698 4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-(2-(2-(piperidin-1-yl)ethylamino)quinazolin-6-yl)benzamide::CHEMBL384942

SMILES Cc1ccc(cc1-c1ccc2nc(NCCN3CCCCC3)ncc2c1)C(=O)Nc1cccc(c1C)C(F)(F)F

InChI Key InChIKey=NSOPDMYYXBLFIE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194698   

TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50194698(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50194698(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50194698(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 173nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50194698(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Jak3 by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed