BDBM50195058 CHEMBL3979286

SMILES Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)Nc2ccc(Cl)cc2)n1

InChI Key InChIKey=SPEDBOZUFYBCIJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195058   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Shionogi

Curated by ChEMBL

LigandBDBM50195058(CHEMBL3979286)Copy SMILESCopy InChI

Affinity DataIC50: 9.5nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/8/2018
Entry Details Article
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