BDBM50195147 (8S,11R,13S,14S,17S)-17-hydroxy-11-(4-hydroxy-3-methyl-phenyl)-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one::CHEMBL426386

SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(O)c(C)c1

InChI Key InChIKey=ZEBLZCMTSQOFIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195147   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195147((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-hydroxy-3-me...)
Affinity DataIC50: 4.5nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195147((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-hydroxy-3-me...)
Affinity DataIC50: 28.6nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed