BDBM50195362 CHEMBL3907289

SMILES COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(N)c(F)c(C)c2Cl)c1

InChI Key InChIKey=PLRPRYDOPJNKDZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195362   

TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50195362(CHEMBL3907289)Copy SMILESCopy InChI

Affinity DataIC50: 47nMAssay Description:Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/9/2018
Entry Details Article
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TargetHistone-lysine N-methyltransferase 2A/Retinoblastoma-binding protein 5/Set1/Ash2 histone methyltransferase complex subunit ASH2/WD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50195362(CHEMBL3907289)Copy SMILESCopy InChI

Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant MLL1 (unknown origin) interaction with recombinant ASH2L/RBBP5/WDR5 (unknown origin) assessed as decrease in histone methyl...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/9/2018
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL