BDBM50195494 (4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan-1-yl)methanone::CHEMBL220436

SMILES Nc1c(Cl)cc(cc1Cl)C(=O)N1CCCN(Cc2ccccc2)CCC1

InChI Key InChIKey=KBTSJKVYWPZTCV-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50195494   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195494((4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan...)
Affinity DataKi:  53nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195494((4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan...)
Affinity DataKi:  210nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195494((4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan...)
Affinity DataIC50: 960nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195494((4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195494((4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed