BDBM50195878 1-(4-(4-amino-7-phenylfuro[3,2-c]pyridin-3-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea::CHEMBL241681

SMILES Nc1ncc(-c2ccccc2)c2occ(-c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12

InChI Key InChIKey=FCCZSKATTXDLOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50195878   

TargetEphrin type-B receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195878(1-(4-(4-amino-7-phenylfuro[3,2-c]pyridin-3-yl)phen...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human EphB4 by scintillation proximity methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195878(1-(4-(4-amino-7-phenylfuro[3,2-c]pyridin-3-yl)phen...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant GST-6XHis-VEGFR2 by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195878(1-(4-(4-amino-7-phenylfuro[3,2-c]pyridin-3-yl)phen...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant GST-Tie2 by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed