BDBM50196132 CHEMBL217203::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine

SMILES CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1

InChI Key InChIKey=OFZVRVWUVPCFQQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196132   

TargetAlpha-2C adrenergic receptor(Human)
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196132([4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-te...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2C expressed in S115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196132([4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-te...)
Affinity DataKi:  5nMAssay Description:Binding affinity to human cloned Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196132([4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-te...)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2B expressed in S115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196132([4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-te...)
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2A expressed in S115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed