BDBM50196351 1-(4-tert-Butyl-benzyl)-3-(4-hydroxy-3-methoxy-benzyl)-thiourea::1-(4-tert-butylbenzyl)-3-(4-hydroxy-3-methoxybenzyl)thiourea::CHEMBL246648

SMILES COc1cc(CNC(=S)NCc2ccc(cc2)C(C)(C)C)ccc1O

InChI Key InChIKey=MRDJEHJOSCNEAJ-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50196351   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196351(1-(4-tert-Butyl-benzyl)-3-(4-hydroxy-3-methoxy-ben...)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]RTX from rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196351(1-(4-tert-Butyl-benzyl)-3-(4-hydroxy-3-methoxy-ben...)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]RTX from rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1/2/4(Rat)
Sandoz Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50196351(1-(4-tert-Butyl-benzyl)-3-(4-hydroxy-3-methoxy-ben...)
Affinity DataEC50:  510nMAssay Description:Compound tested in vitro for [Ca2+] influx into neonatal rat dorsal root ganglia (DRG)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196351(1-(4-tert-Butyl-benzyl)-3-(4-hydroxy-3-methoxy-ben...)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at rat TRPV1 expressed in CHO cells assessed as calcium uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196351(1-(4-tert-Butyl-benzyl)-3-(4-hydroxy-3-methoxy-ben...)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at rat TRPV1 expressed in CHO cells assessed as maximal calcium uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed