BDBM50196709 1-(2,4-dichlorobenzyl)-3-(1H-indazol-5-yl)urea::CHEMBL224887::N-(2,4-dichlorobenzyl)-N0-(1H-5-indazolyl)urea

SMILES Clc1ccc(CNC(=O)Nc2ccc3[nH]ncc3c2)c(Cl)c1

InChI Key InChIKey=QFYWQJFCTRAAGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196709   

TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196709(N-(2,4-dichlorobenzyl)-N0-(1H-5-indazolyl)urea | 1...)
Affinity DataIC50: 220nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196709(N-(2,4-dichlorobenzyl)-N0-(1H-5-indazolyl)urea | 1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed