BDBM50197103 (2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine::CHEMBL384474

SMILES N[C@@H]([C@@H]1CC[C@@H]1C(O)=O)C(O)=O

InChI Key InChIKey=SRAFHGOPGVYULO-WISUUJSJSA-N

Data  5 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197103   

TargetGlutamate receptor 3(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  330nMAssay Description:Binding affinity to full length rat GluA3More data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity to rat GluA3-LBD (GluK3-S1S2)More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed